CBD 101

Researched studies on CBD


Acne is a skin condition caused by inflammation of your skin glands or hair follicles in conjunction with Sebum, a waxy, oily substance. This can cause pimples and scaring, typically on the face, forehead, chest, upper back or shoulders. Most people have acne at some point in their life, typically between ages 11 and 30. CBD oil may help reduce various types of Acne due to its ability to adjust how our body creates Sebum. Research & Studies has found that CBD assisted in preventing these cells from creating too much of the oily Sebum which causes Acne.


ADD, or Attention Deficit Disorder, refers to a range of behavioral disorders occurring primarily in children. The most common symptoms are poor concentration and impulsiveness.
ADHD, or Attention Deficit Hyperactivity Disorder additionally includes constant movement and fidgeting. CBD might help with managing specific symptoms of ADD/ADHD that many people experience. Some people with ADHD struggle with anxiety which can make their symptoms worse. There is some evidence to show that CBD oil may help with symptoms of anxiety. Claims made by researchers from studies back in 2016 report that CBD may help with anxiety and sleep problems in children. Ongoing research is exploring these disorders.

Addiction & Alcoholism

Addiction is defined by the inability to consistently abstain from a substance (such as Opiates) or behavior, despite substantial medical and physical harm to yourself. Alcoholism refers to the addiction to alcohol, in particular.

ALS (Amyotrophic Lateral Sclerosis)

Cannabinoids may help delay disease progression and prolong survival in about 10% of ALS paitents researched. Only a few studies have investigated the effect of cannabinoids in human patients, which makes it difficult to interpret the results. It has been shown cannabinoids are capable of delaying ALS progression.

Alzheimer's Disease

ALS and CBD Studies are still in their infancy. While CBD may be able to help with some symptoms we are awaiting conducted studies to find out for sure if CBD can delay or prevent those with Alzheimer's Disease.


Cannabinioids have been shown to increase appetite at least 73% of patients in recent studies. By increasing appetite and increasing mood and behavior CBD may be able to assist those suffering with Anorexia.

Antibiotic Resistance

Researchers at the University of Queensland’s Institute for Molecular Bioscience, discovered through a series of test-tube experiments that CBD is capable of killing numerous strains of bacteria, even the ones such as VRSA, VISA, and MRSA.

These strains have developed resistance to existing antibiotics over the years, but they didn’t develop any resistance to CBD. Since the strains were exposed to CBD for 20 days, researches concluded that this cannabis compound has the ability to outmanoeuvre the whole process of superbug development. Mark Blaskovich, team leader of this research, states that there’s no doubt that CBD has a certain unique mechanism of action which works against bacteria that have developed resistance to other antibiotics, but has to admit they still don’t know how this unique manoeuvre works.

Two types of research confirmed CBD’s power to fight superbugs. Due to CBD’s ability to disrupt the layers of liquid around bacteria cells – called biofilm – which antibiotics had difficulty in penetrating, it’s obvious that it’s very unlikely to cause resistance, but only to some extent.

The Australian researches discovered that CBD is effective against Gram-positive bacteria strains which cause conditions such as pneumonia and skin infections. But they’ve also discovered that it’s not effective against Gram-negative strains associated with gastrointestinal disorders such as Escherichia Coli and salmonella. Nevertheless, the United Kingdom research did make progress with Escherichia Coli, so this point of resistance may depend on further research.


A 2010 study found that cannabidiol could reduce symptoms of social anxiety in people with social anxiety disorder (SAD). Brain scans of participants revealed changes in blood flow to the regions of the brain linked to feelings of anxiety.


A 2006 Study showed that CBD directly helps inflammation and pain through the CB2 receptors found in the endocannabinoid system. The most recent studies as of 2017 find that CBD may also assist with OA Joint Pain. 


CBD is a very potent bronchodilator and useful in the treatment of Asthma. CBD by any form has shown to result in decreased airway resistance.


The role of CB2 receptor activation on atherosclerosis occurrence has been studied and it was shown that CB2 stimulation leads to attenuation of the inflammatory response in the pathogenesis of atherosclerosis. Various investigations on models of human diseases support the idea that CBD weakens the inflammation beyond the known antioxidant properties of CBD. The therapeutic utility of CBD is a relatively new area of investigation that will result in new discoveries on the interaction between inflammation and oxidative stress and the endocannabinoid system (ECS), a relationship that highlights the tissue and organ damage in many human disorders, including atherosclerosis.

Autism Spectrum Disorder (ASD)

There are currently ongoing observational studies between the links of Cannabinoids and Autism. More studies are needed to conclusively say that CBD does help treat austim in children and adults. Read more about those studies here.

Autoimmune Diseases

Autoimmune diseases effect roughly 53 to 80 million, CBD helps regulation of inflammation response, if this is regulated, there will be less likelihood of an autoimmune attack. More studies will be conducted to examine the particular role of cannabinoids for autoimmune disorders.


Individuals experiencing symptoms of bipolar disorders should consult with a medical professional before starting or changing treatment. There are not enough studies correlated between CBD and bipolar disorders, some participants of recent studies have reported increased mood and less depressive episodes.


There have been several studies support CBD and reduction in tumor growth. Participants have reported inhibition of colorectal cancer cells and found that CBD significantly reduced breast cancer cell proliferation and invasion. Read more on these studies here.

Colitis & Crohn's Disease

CBD effectively treats inflammation making it a very useful tool in treating those that suffer from ulcerative colitis.
A study of adult participants were compared in recent studies, 8 of 31 participants reported better quality of life.


Anxiety and Depression Association of America recently came out with a very interesting article relating to CBD and Depression. They state while studies do need to continue, there is evidence that CBD may help due its non-psychoactive and neuroprotective properties.

*Disclaimer: While CBD may offer some benefits, it isn’t a replacement for prescribed medication. DO NOT stop taking prescribed medication, especially antidepressants, without talking to your healthcare provider first.


What we do know is that the body’s endocannabinoid system plays an important part in the regulating energy metabolism, which is important to know for those who are living with diabetes. The endocannabinoid system plays an integral role in how the body responds to insulin, increasing or decreasing insulin sensitivity. This is critically important for those who are taking insulin because it could mean that their blood sugars could rise or fall unexpectedly, making tight control more difficult to achieve. CBD responds differently to every individual and more science is needed to see how CBD effects Diabetes.

Endocrine disorders

Cannabionoids have been researched to affect the Endocrine system through the CB1 receptors. CBD has potential to regulate hormone production and relieve disorders such as tumors that directly affect the thyroid glands. Research in this area is extremely preliminary, but it signals that cannabinoids may be able to influence the endocrine system and thyroid. Research in this field is very preliminary.

Epilepsy & Seizures

While the FDA has approved a single formula for Epilepsy, many studies have been conducted that related to Epilepsy, according National Library of Medicine, CBD shows protective activity in pilocarpine models of temporal lobe seizures and in the penicillin and cobalt models of focal seizures in rats. Find more here.


According to Medical News Today, Anecdotal data suggests that taking CBD oil may alleviate symptoms of fibromyalgia in some people. CBD has been found to effectively reduce pain, improve sleep, and diminish refractory pain in patients with fibromyalgia, migraine, irritable bowel syndrome, and similar conditions involving chronic pain. A 2016 study suggests that a lack of endocannabinoids (neurotransmitters that bind to cannabinoid receptors) may be at the root of chronic pain syndromes, including migraines and fibromyalgia. Taking CBD may correct this deficiency, explaining the compound's success in alleviating chronic pain.

Heart Disease

CBD has anti-inflammatory and antioxidative properties that may be able to reduce risk factors, like high blood pressure that can lead to heart disease. It may also be able to reduce the risk of related conditions, such as stroke.


Affecting over 40 million individuals, HIV is extremely detrimental and incurable disease. Research shows that CBD HIV supplements may help the body in the fight against the virus and suppresses the symptoms associated with it. Apart from managing the patient’s symptoms, the treatment can also help in slowing down the progression of the virus not to mention aiding medication by reducing side effects.

Huntington's Disease (HD)

Preliminary studies indicate that not only does cannabis provide relief from symptoms, but may slow down the progression of HD. CBD has been shown to have neuro-protective properties, which can resist the deterioration of neurons in the brain and spinal cord.


Studies have shown that CBD may help reduce chronic pain by interacting with the endocannabinoid receptor activity, reducing inflammation and interacting with neurotransmitters.

Inflammatory Bowel Disorder (IBD)

Studies have shown cannabinoid and cannabinoid-like compounds. such as CBD have been shown to reduce intestinal permeability in vivo and may thus be potentially useful in the treatment of IBD and related conditions.

Irritable Bowel Syndrome (IBS)

Research has shown that CBD and cannabinoid-like properties can assist with inflammation that directly affects those that suffer with IBS. Medical professionals do warn to keep track of milligrams taken when using CBD for IBS and to talk with your physician before taking CBD with any medication for clearance.

Kidney Disease

Current research on CBD for kidney disease is neither exhaustive nor conclusive, but it is promising. Many of the symptoms and conditions connected to kidney disease have been helped or impacted by CBD in some way. If you’re considering trying CBD to manage kidney disease, alone or in tandem with your current kidney disease medication, first speak to your doctor. While CBD oil is considered moderately safe, it can interact with some medications in a way that’s dangerous to the liver.

Liver Disease

Migraines / Headaches

While there are currently no published studies that examine the effects of CBD as a single ingredient on migraine. CBD does assist with inflammation that may reduce headaches.

Mood Disorders

A 2019 animal study found that CBD has a fast and sustained antidepressant-like effect. CBD may also result in fewer side effects than antidepressant medication. Insomnia, sexual dysfunction, mood swings, and agitation are common side effects of antidepressants.

Motion Sickness

CBD derived from hemp is high in protein and omegas that greatly impact brain function. Some studies suggest that CBD can help you calm down and get a better understanding of your situation making you feel better faster.

Multiple Sclerosis (MS)

CBD is known to exhibit both anti-inflammatory and neuroprotective effects against known and suspected autoimmune diseases, although much research is needed it was theorized that medicinal CBD could also be of benefit to MS patients.


CBD interacts with serotonin releasing receptors, and when given in relatively small doses has been shown to help alleviate both nausea and vomiting. CBD can also be effective in easing anxiety, which can help patients manage the angst of chronic nausea.1



CBD helps block off the CB1 receptors, meaning that it might reduce the risk of obesity

OCD (Obsessive Compulsive Disorder)

CBD may able to reduce the severity of obsessive and/or compulsive behaviors in children, adults and even pets. Antipsychotic CBD is also shown to effectively reduce the symptoms of more chronic conditions such as bipolar disorder schizophrenia, and manic depression.

Osteoporosis/Bone Health

Studies have shown that CBD significantly repairs bone damage and at a much faster rate in animals tested with CBD. CBD has been shown to assist in bone growth


A study in US National Library of Medicine National Institutes of Health suggests that due to the anti-inflammation properties of CBD, that it may greatly reduce chronic pain and arthritis.

Parkinson's Disease

A healthy, natural alternative to traditional medications is becoming more and more accessible for persons suffering the effects of Parkinson’s disease. Studies show that CBD, a Cannabidiol also referred to as CBD-rich cannabis, may offer much-needed relief for the debilitating symptoms of Parkinson’s. CBD is also gaining momentum as a treatment for other health-related conditions including Alzheimer’s disease, epilepsy, anxiety, and chronic pain. Studies are ongoing.

Prion Disease (Mad Cow)

Research is continuing to examine the likelihood of cannabinoids protecting neurological connectivity with studies supporting a favorable likelihood of CBD guarding nerve cells against progressive deterioration caused by prions. Scientists have observed CBD working harmoniously with the peripheral nervous system lower the production of protease-resistant prion proteins (PrPres) in the brain.

PTSD (Post Traumatic Stress Disorder)

CB1 cannabinoid receptors in the body help ease anxiety and traumatic memories. Many more studies are being conducted to support this theory. If you or someone you know suffers from PTSD, please be sure to consult medical physician before using CBD or mixing with any medications.

*Premium Care CBD does not suggest discontinuing any medication relating to PTSD or depression*


Studies suggest that CBD has a moderately high potential to assist with mental symptoms of Schizophrenia.


Comprised of endogenous compounds that bind to CB1 and CB2 receptors – which are expressed in all types of skin cells, the ECS plays a vital role in maintaining skin homeostasis through a signaling mechanism that promotes healthy skin renewal and barrier function, due to this reason, CBD may be effective in treating Scleroderma.

Sickle Cell Anemia

According to Harvard University, “CBD inhibits inflammatory and neuropathic pain, two of the most difficult types of chronic pain to treat,” making it an ideal option for the chronic pain associated with sickle cell anemia.

Nerve pain is something commonly experienced by individuals with sickle cell anemia. CBD may be effective at relieving this type of pain. Glycine receptors are inhibitory receptors located throughout the central nervous system. These receptors play a central role in the perception of nerve pain in particular. Studies have indicated that CBD can potentiate, or increase the effects of, these receptors, reducing the severity of nerve pain.

Skin Conditions

CBD has been shown to be helpful at easing eczema, psoriasis, acne, and some symptoms of fibromyalgia. Also at soothing and moisturizing redness and bumps.

Sleep Disorders

According to sleepassociation.org- A study published in the Permanente Journal, 72 adults with anxiety and poor sleep were involved. The participants completed anxiety and sleep assessments at the start of the study and at the first-month follow-up. Study participants were given 25 mg in capsule form of CBD. Those that had predominately sleep complaints took the dose in the evening. Participants that had anxiety as the predominant complaint took the CBD in the morning.

After the first month, anxiety scores decreased in 79 percent of the people. Sleep scores improved in 66 percent of the participants, which indicated less trouble sleeping. The results suggest that CBD decreased sleep difficulties in many of the participants. But while the decrease in anxiety symptoms remained steady for the duration of the study, the sleep scores fluctuated over time.

Spinal Cord Injury

Studies have shown CBD relaxes and enables sleep patterns that assist in faster recovery from Spinal Cord Injury. More research is needed in long term effects from this condition.


Many studies have shown that CBD can be a positive solution for people suffering stress and social anxiety. CBD directly interacts with CB1 receptors and assist with boosting the endocannabinoid system specifically through receptor 5-HT1a. Learn more here.


Tramatic Brain Injury

CBD has been researched thoroughly showing to assist in recovery from TMI. Attaching to CB1 and CB2 receptors and assisting the brain in memory protection. Learn More

Weight Loss

Millions suffer from obesity and research shows CBD may be able to combat fatty tissue cells by activating your body's natural ECS system and boosting metabolism. Learn more about this study.


CBD for overall wellness has been studied in several ways. One main reason being that Protein and Omegas 3,6, and 9 naturally occur in hemp plants.

DISCLAIMER: Premiumcare.com/cbd-101 is an information database accumulated by research and studies of third party resources. This site does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.